What Is Molecular Basis?

What is the molecular definition of an acid?

An Arrhenius acid is a compound that increases the concentration of H+ ions that are present when added to water.

These H+ ions form the hydronium ion (H3O+) when they combine with water molecules.

This process is represented in a chemical equation by adding H2O to the reactants side.

HCl(aq)→H+(aq)+Cl−(aq).

What are the three types of mutations?

There are three types of DNA Mutations: base substitutions, deletions and insertions. Single base substitutions are called point mutations, recall the point mutation Glu —–> Val which causes sickle-cell disease. Point mutations are the most common type of mutation and there are two types.

What is molecular genetics used for?

Species identification – Molecular genetic tests can be used to identify the species and sometimes even the population of origin from a sample (feather, tissue, feces, hair) of unknown origin.

What is an example of molecular genetics?

For example, the gene MECP2 (methyl CpG binding protein 2) encodes a protein that binds to specific methylated regions of DNA and contributes to the silencing of those sequences. Mutations that impair the MECP2 gene can lead to Rett syndrome.

Is Sickle Cell Anemia a molecular disease?

“Sickle Cell Anemia, a Molecular Disease” is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.

What are the molecular bases?

DNA is made of a long sequence of smaller units strung together. There are four basic types of unit: A, T, G, and C. These letters represents the type of base each unit carries: adenine, thymine, guanine, and cytosine. The sequence of these bases encodes instructions.

What is the molecular basis for genes?

The molecular basis of gene expression. What Is the Genetic Code? the one gene–one protein hypothesis. The information flow that controls protein synthesis passes from DNA to RNA to the protein synthetic machinery.

What is molecular basis of mutation?

In gene mutation, one allele of a gene changes into a different allele. Because such a change takes place within a single gene and maps to one chromosomal locus (“point”), a gene mutation is sometimes called a point mutation.

What are the chemical differences between DNA and RNA molecules?

DNA contains the sugar deoxyribose, while RNA contains the sugar ribose. The only difference between ribose and deoxyribose is that ribose has one more -OH group than deoxyribose, which has -H attached to the second (2′) carbon in the ring. DNA is a double-stranded molecule, while RNA is a single-stranded molecule.

Which medical conditions are inherited?

Almost all known conditions have a genetic basis. For example: around 5 per cent of cancers are passed down through families. early onset of conditions such as Alzheimer’s disease, cancer and osteoporosis are often because there is a family history of the condition.

What is molecular basis of disease?

BBA Molecular Basis of Disease addresses the biochemistry and molecular genetics of disease processes and models of human disease. … Manuscripts should emphasize the underlying mechanisms of disease pathways and provide novel contributions to the understanding and/or treatment of these disorders.

What are molecular diseases?

A disease in which there is an abnormality in or a deficiency of a particular molecule, such as hemoglobin in sickle cell anemia.

What are the four basic units of DNA?

There are 4 different bases in DNA: Guanine (G), Adenine (A), Cytosine (C) and Thymine (T). The sequence in which the bases occur is a code that contains information.